Burdol 
Diamond IV 
Challenger Who wins Ambessa vs Vayne?
In the 6 high-elo VODs on MID.GG, Ambessa won 67%.
Ambessa vs Vayne at a glance
VOD library Favoured Small sample
In 6 high-elo games (latest patch 16.16), Ambessa won 67% against Vayne, so the matchup looks favoured in our library. The average game ended 5.2/4.8/5.0 for Ambessa. That is a small sample, so treat it as a starting point.
Pro build
The most played Ambessa setup into Vayne takes Electrocute (Domination and Resolve) and builds Eclipse. It shows up in 3 of 6 games with a 67% win rate. The main alternative is Grasp of the Undying (1 game).
How they built Ambessa into Vayne
Taken from the 6 VODs on this page, patch 16.16, 16.15, 16.14.
Most played setup
Runes
Core items
One-off setup
Runes
Core items
Streamers who play Ambessa
Every streamer in the library with ranked Ambessa games, most games first. Each links to their VODs on MID.GG.
koalaa_lol 
Grandmaster
Common questions about Ambessa vs Vayne
What should Ambessa build against Vayne?
The most-played setup is the Electrocute rune page, taken in 3 of the 6 high-elo VODs on MID.GG, with Eclipse as its most common core items.
Which pros and streamers play Ambessa?
Burdol (73 games), Doran (48) and DuDu (33) have the most Ambessa VODs on MID.GG, each with their runes, build and full timeline.
Latest Ambessa vs Vayne games
The most recent games in this matchup, newest first.
- Defeat 3/8/5koalaa_lol Grandmaster · Top Patch 16.16
- Victory 8/6/10koalaa_lol Grandmaster · Top Patch 16.15
- Victory 6/7/7DuDu
Master · Top Patch 16.14 - Defeat 2/6/1DuDu Grandmaster · Top Patch 16.13
- Victory 3/2/7Doran Master · Top Patch 16.5
- Victory 9/0/0Burdol Grandmaster · Top Patch 16.1
