Master 
Peyz 
Grandmaster 
Who wins Kai'Sa vs Senna?
Kai'Sa wins 47.8% of 523 NA and EUW ranked games against Senna in bot lane, against 49.1% in that role overall. MID.GG has 3 high-elo VODs of this matchup so far, not enough games yet to call it.
Kai'Sa vs Senna at a glance
Ranked record In line
Across 523 NA and EUW ranked games in bot lane, Kai'Sa wins 47.8% against Senna, in line with the 49.1% Kai'Sa wins in that role overall.
VOD library Not enough games yet
In our library of 3 high-elo VODs (latest patch 25.17), Kai'Sa won 67% against Senna and averaged 7.3/2.0/4.0. That is not enough games yet to say who the matchup favours.
Pro build
One Kai'Sa setup into Senna takes Lethal Tempo (Precision and Inspiration) and builds Kraken Slayer, Guinsoo's Rageblade and Nashor's Tooth. It shows up in 1 of 3 games. The main alternative also takes Lethal Tempo but runs Presence of Mind and Legend: Bloodline (1 game).
Solo kills by level
A solo kill is a kill on the lane opponent with no assist. The bars over each champion above count them by champion level, from 523 NA and EUW ranked games in bot lane; the amber marks are where that champion's kills usually fall.
Kai'Sa's solo kills on Senna Fewer kills
Kai'Sa gets 0.4 solo kills per game against Senna, fewer than the 0.5 Kai'Sa averages in bot lane, and 11% of them come before level 6, about the usual 12%.
How they built Kai'Sa into Senna
Taken from the 3 VODs on this page, patch 25.11–25.17.
One-off setup
Runes
Core items
One-off setup
Runes
Core items
Streamers who play Kai'Sa
Every streamer in the library with ranked Kai'Sa games, most games first. Each links to their VODs on MID.GG.
dunlol 
Challenger
Common questions about Kai'Sa vs Senna
What should Kai'Sa build against Senna?
No rune page repeats yet in the 3 high-elo VODs on MID.GG; one game ran the Lethal Tempo rune page, building Kraken Slayer, Guinsoo's Rageblade and Nashor's Tooth first.
Latest Kai'Sa vs Senna games
The most recent games in this matchup, newest first.
- Victory Clid Challenger
6/0/4K / D / A Patch 25.17 BotWatch in the app - Defeat Stixxay Challenger 4/5/3K / D / A Patch 25.15 BotWatch in the app
- Victory Clid Challenger 12/1/5K / D / A Patch 25.11 BotWatch in the app
Related pages
