Who wins Vayne vs Cassiopeia?
MID.GG has 2 high-elo VODs of this matchup so far, not enough games yet to call it.
Vayne vs Cassiopeia at a glance
VOD library Not enough games yet
In 2 high-elo games (latest patch 26.18), Vayne won 50% against Cassiopeia. The average game ended 5.5/8.5/3.5 for Vayne. That is not enough games yet to say who the matchup favours.
Pro build
The most played Vayne setup into Cassiopeia takes Lethal Tempo (Precision and Domination) and builds Kraken Slayer, Stormrazor and Lord Dominik's Regards. It shows up in 2 of 2 games with a 50% win rate.
How they built Vayne into Cassiopeia
Taken from the 2 VODs on this page, patch 26.17 and 26.18.
Most played setup
Runes
Core items
Streamers who play Vayne
Every streamer in the library with ranked Vayne games, most games first. Each links to their VODs on MID.GG.
loltyler1 
Grandmaster 
Deft 
Challenger 
GeneralSniper Grandmaster 
DuDu 
Master 
Broxah Master
Common questions about Vayne vs Cassiopeia
What should Vayne build against Cassiopeia?
The most-played setup is the Lethal Tempo rune page, taken in 2 of the 2 high-elo VODs on MID.GG, with Kraken Slayer, Stormrazor and Lord Dominik's Regards as its most common core items.
Latest Vayne vs Cassiopeia games
The most recent games in this matchup, newest first.
- Defeat reptile9lol Master
2/9/1K / D / A Patch 26.18 TopWatch in the app - Victory reptile9lol Master 9/8/6K / D / A Patch 26.17 TopWatch in the app
Related pages
