Peyz 
Challenger 
Who wins Kai'Sa vs Karthus?
Kai'Sa wins 47.2% of 436 NA and EUW ranked games against Karthus in bot lane, against 49.0% in that role overall. In the 10 high-elo VODs on MID.GG, Kai'Sa won 40%.
Kai'Sa vs Karthus at a glance
Ranked record In line
Across 436 NA and EUW ranked games in bot lane, Kai'Sa wins 47.2% against Karthus, in line with the 49.0% Kai'Sa wins in that role overall.
VOD library Uphill
In our library of 10 high-elo VODs (latest patch 26.19), Kai'Sa won 40% against Karthus and averaged 6.6/6.4/5.4.
Pro build
The most played Kai'Sa setup into Karthus takes Lethal Tempo (Precision and Inspiration) and builds Kraken Slayer, Guinsoo's Rageblade and Nashor's Tooth. It shows up in 3 of 10 games with a 33% win rate. The main alternative is Dark Harvest (2 games).
Solo kills by level
A solo kill is a kill on the lane opponent with no assist. The bars over each champion above count them by champion level, from 436 NA and EUW ranked games in bot lane; the amber marks are where that champion's kills usually fall.
Kai'Sa's solo kills on Karthus More kills
Kai'Sa gets 0.8 solo kills per game against Karthus, more than the 0.5 Kai'Sa averages in bot lane, and 13% of them come before level 6, about the usual 11%.
Karthus's solo kills on Kai'Sa
Karthus gets 0.7 solo kills per game against Kai'Sa, in line with the 0.6 Karthus averages in bot lane, and 15% of them come before level 6, about the usual 16%.
How they built Kai'Sa into Karthus
Taken from the 10 VODs on this page, patch 26.17–26.19.
Most played setup
Runes
Core items
Alternative setup
Runes
Core items
Streamers who play Kai'Sa
Every streamer in the library with ranked Kai'Sa games, most games first. Each links to their VODs on MID.GG.
stunt 
Grandmaster
Common questions about Kai'Sa vs Karthus
What should Kai'Sa build against Karthus?
The most-played setup is the Lethal Tempo rune page, taken in 3 of the 10 high-elo VODs on MID.GG, with Kraken Slayer, Guinsoo's Rageblade and Nashor's Tooth as its most common core items.
Latest Kai'Sa vs Karthus games
The most recent games in this matchup, newest first.
- Victory Gosu
Master 
13/1/7K / D / A Patch 26.19 BotWatch in the app - Defeat Assassadin Master 1/6/8K / D / A Patch 26.19 BotWatch in the app
- Victory xFSN_Saber Grandmaster 8/3/4K / D / A Patch 26.18 BotWatch in the app
- Defeat Gosu Master 8/16/4K / D / A Patch 26.17 BotWatch in the app
- Defeat Gosu Master 8/9/7K / D / A Patch 26.17 BotWatch in the app
- Defeat xFSN_Saber Master 9/8/2K / D / A Patch 26.16 BotWatch in the app
- Victory xFSN_Saber Master 6/3/6K / D / A Patch 26.15 BotWatch in the app
- Victory Peyz Grandmaster 3/0/3K / D / A Patch 14.4 BotWatch in the app
- Defeat Deft Master 8/6/4K / D / A Patch 14.3 BotWatch in the app
- Defeat Peyz Master 2/12/9K / D / A Patch 14.2 BotWatch in the app
Related pages
