loltyler1 
Clid 
Challenger 
Who wins Karthus vs Zac?
Karthus wins 47.6% of 164 NA and EUW ranked games against Zac in jungle, against 49.1% in that role overall. In the 5 high-elo VODs on MID.GG, Karthus won 40%.
Karthus vs Zac at a glance
Ranked record Below average
Across 164 NA and EUW ranked games in Jungle, Karthus wins 47.6% against Zac, 1.5 points lower than the 49.1% Karthus wins in that role overall.
VOD library Uphill Small sample
In our library of 5 high-elo VODs (latest patch 16.19), Karthus won 40% against Zac and averaged 4.4/5.8/9.4. That is a small sample, so treat it as a starting point.
Pro build
The most played Karthus setup into Zac takes Dark Harvest (Domination and Sorcery) and builds Liandry's Torment, Blackfire Torch and Void Staff. It shows up in 2 of 5 games with a 0% win rate. The main alternative is First Strike (1 game).
How they built Karthus into Zac
Taken from the 5 VODs on this page, patch 16.19, 15.1, 14.14.
Most played setup
Runes
Core items
One-off setup
Runes
Core items
Streamers who play Karthus
Every streamer in the library with ranked Karthus games, most games first. Each links to their VODs on MID.GG.
Common questions about Karthus vs Zac
What should Karthus build against Zac?
The most-played setup is the Dark Harvest rune page, taken in 2 of the 5 high-elo VODs on MID.GG, with Liandry's Torment, Blackfire Torch and Void Staff as its most common core items.
Which pros and streamers play Karthus?
loltyler1 (392 games), Karhus (310) and lolmalice (203) have the most Karthus VODs on MID.GG, each with their runes, build and full timeline.
Latest Karthus vs Zac games
The most recent games in this matchup, newest first.
- Victory 6/4/11Karhus
Master · Jungle Patch 16.19 - Defeat 5/9/12Clid
Diamond II · Jungle Patch 15.1 - Defeat 2/7/4Clid
Grandmaster · Jungle Patch 14.14 - Victory 5/2/12Clid Grandmaster · Jungle Patch 14.13
- Defeat 4/7/8Clid Grandmaster · Jungle Patch 14.13
