Karthus vs Vayne at a glance
Ranked record Below average
Across 96 NA and EUW ranked games in Bot lane, Karthus wins 45.8% against Vayne, 7.2 points lower than the 53.0% Karthus wins in that role overall. That is a small sample, so treat it as a starting point.
VOD library Uphill
In our library of 13 high-elo VODs (latest patch 16.18), Karthus won 46% against Vayne and averaged 6.2/7.0/9.8.
Pro build
The most played Karthus setup into Vayne takes Dark Harvest (Domination and Precision) and builds Liandry's Torment and Shadowflame. It shows up in 11 of 13 games with a 55% win rate. The main alternative also takes Dark Harvest but runs Grisly Mementos (2 games).
How they built Karthus into Vayne
Taken from the 13 VODs on this page, patch 16.18, 16.7, 13.24.
Most played setup
Runes
Core items
Alternative setup
Runes
Core items
Latest Karthus vs Vayne games
The most recent games in this matchup, newest first.
- Defeat 7/6/5loltyler1
Master I · Bot Patch 16.18 - Defeat 6/10/14loltyler1 Master I · Bot Patch 16.7
- Victory 5/6/9loltyler1 Master I · Bot Patch 13.24
- Victory 5/1/6loltyler1 Master I · Bot Patch 13.24
- Victory 17/11/19loltyler1 Master I · Bot Patch 13.24
- Defeat 3/5/2loltyler1 Master I · Bot Patch 13.24
- Victory 4/5/11loltyler1 Master I · Bot Patch 13.24
- Defeat 6/13/11loltyler1 Master I · Bot Patch 13.24
- Defeat 5/5/6loltyler1 Master I · Bot Patch 13.24
- Defeat 2/8/4loltyler1 Master I · Bot Patch 13.17
- Defeat 6/7/5loltyler1 Master I · Bot Patch 13.13
- Victory 12/9/19loltyler1
Diamond I · Bot Patch 13.6 - Victory 3/5/17loltyler1 Master I · Bot Patch 12.17
