Who wins Pantheon vs Rek'Sai?
MID.GG has 4 high-elo VODs of this matchup so far, not enough games yet to call it.
In 4 high-elo games (latest patch 26.22), Pantheon won 50% against Rek'Sai. The average game ended 6.0/3.5/4.0 for Pantheon. That is not enough games yet to say who the matchup favours.
One Pantheon setup into Rek'Sai takes Conqueror (Precision and Inspiration) and builds Sundered Sky, Black Cleaver and Maw of Malmortius. It shows up in 1 of 4 games. The main alternative also takes Conqueror but runs Legend: Haste and Cut Down (1 game).
Taken from the 4 VODs on this page, patch 26.12–26.22.
Every streamer in the library with ranked Pantheon games, most games first. Each links to their VODs on MID.GG.
MID.GG has 4 high-elo VODs of this matchup so far, not enough games yet to call it.
No rune page repeats yet in the 4 high-elo VODs on MID.GG; one game ran the Conqueror rune page, building Sundered Sky, Black Cleaver and Maw of Malmortius first.
The most recent games in this matchup, newest first.

